Autoimmunity and Gastric Cancer

نویسندگان

  • Nicola Bizzaro
  • Antonio Antico
  • Danilo Villalta
چکیده

Alterations in the immune response of patients with autoimmune diseases may predispose to malignancies, and a link between chronic autoimmune gastritis and gastric cancer has been reported in many studies. Intestinal metaplasia with dysplasia of the gastric corpus-fundus mucosa and hyperplasia of chromaffin cells, which are typical features of late-stage autoimmune gastritis, are considered precursor lesions. Autoimmune gastritis has been associated with the development of two types of gastric neoplasms: intestinal type and type I gastric carcinoid. Here, we review the association of autoimmune gastritis with gastric cancer and other autoimmune features present in gastric neoplasms.

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عنوان ژورنال:

دوره 19  شماره 

صفحات  -

تاریخ انتشار 2018